Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 19/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4187269 | 0.97 | FASN (0.57) | FASN | |
| SCHEMBL4181148 | 0.87 | CA12 (0.59) | FASNCA12CA1CA2CA7 | |
| SCHEMBL4175298 | 0.87 | FASN (0.59) | FASN | |
| SCHEMBL4184616 | 0.87 | FASN (0.61) | FASN | |
| SCHEMBL4170791 | 0.86 | FASN (0.60) | FASN | |
| SCHEMBL4190052 | 0.85 | FASN (0.55) | FASN | |
| SCHEMBL4184710 | 0.85 | FASN (0.55) | FASNCA12CA1CA2CA7 | |
| SCHEMBL4179408 | 0.85 | FASN (0.59) | FASN | |
| SCHEMBL4167169 | 0.85 | FASN (0.59) | FASNCA12CA1CA2CA7 | |
| SCHEMBL4169865 | 0.85 | FASN (0.59) | FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008075070-A1 | SULFONAMIDE DERIVATIVES FOR THERAPEUTIC USE AS FATTY ACID SYNTHASE INHIBITORS | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | disclosed |