Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | INPP5D | Q92835 | 1/20 | 0.57 |
| ▸ | CDC25A | P30304 | 4/20 | 0.54 |
| ▸ | POLA1 | P09884 | 1/20 | 0.53 |
| ▸ | NPC1L1 | Q9UHC9 | 3/20 | 0.52 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | OSBP | P22059 | 1/20 | 0.48 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.48 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.48 |
| ▸ | FNTA | P49354 | 1/20 | 0.48 |
| ▸ | FNTB | P49356 | 1/20 | 0.48 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9224303 | 0.94 | CYP2D6 (0.65) | CYP2D6CYP2C19INPP5DCDC25APOLA1 | |
| SCHEMBL28408 | 0.94 | CYP2D6 (0.65) | CYP2D6CYP2C19INPP5DCDC25APOLA1 | |
| SCHEMBL3447573 | 0.94 | CYP2D6 (0.65) | CYP2D6CYP2C19INPP5DCDC25APOLA1 | |
| SCHEMBL133952 | 0.94 | CYP2D6 (0.65) | CYP2D6CYP2C19INPP5DCDC25APOLA1 | |
| Methoxymethane SCHEMBL4786442 | 0.93 | CYP2D6 (0.61) | CYP2D6CYP2C19INPP5DCDC25APOLA1 | |
| Water SCHEMBL4949873 | 0.93 | CYP2D6 (0.64) | CYP2D6CYP2C19INPP5DCDC25APOLA1 | |
| Ether SCHEMBL4736865 | 0.92 | CYP2D6 (0.58) | CYP2D6CYP2C19INPP5DCDC25APOLA1 | |
| SCHEMBL4739574 | 0.90 | CYP2D6 (0.57) | CYP2D6CYP2C19INPP5DCDC25APOLA1 | |
| Epicoprosterol SCHEMBL6519923 | 0.88 | CYP2C19 (0.66) | CYP2D6CYP2C19INPP5DCDC25APOLA1 | |
| SCHEMBL734988 | 0.85 | CYP2D6 (0.53) | CYP2D6CYP2C19INPP5DCDC25ANPC1L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008077247-A1 | COATINGS FOR IMPLANTABLE MEDICAL DEVICES COMPRISING CHOLESTEROL | MIV THERAPEUTICS INC. (CA) | 2008-07-03 | — | — | WO | disclosed |