Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 16/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4172600 | 0.91 | P2RY12 (0.63) | P2RY12CYP3A4CYP2C9CHRM2DRD3 | |
| SCHEMBL4737184 | 0.91 | P2RY12 (0.49) | P2RY12CYP3A4CYP2C9CHRM2DRD3 | |
| SCHEMBL4737254 | 0.91 | P2RY12 (0.58) | P2RY12CYP3A4CYP2C9CHRM2DRD3 | |
| SCHEMBL4852691 | 0.89 | P2RY12 (0.52) | P2RY12CYP3A4CYP2C9CHRM2DRD3 | |
| SCHEMBL4740631 | 0.89 | P2RY12 (0.64) | P2RY12CYP3A4CYP2C9CHRM2DRD3 | |
| SCHEMBL4737929 | 0.86 | P2RY12 (0.63) | P2RY12CYP3A4CYP2C9CHRM2DRD3 | |
| SCHEMBL4175823 | 0.83 | P2RY12 (0.63) | P2RY12CYP3A4CYP2C9CHRM2DRD3 | |
| SCHEMBL4171008 | 0.83 | P2RY12 (0.64) | P2RY12CYP3A4CYP2C9CHRM2DRD3 | |
| SCHEMBL4170985 | 0.82 | P2RY12 (0.61) | P2RY12CYP3A4CYP2C9CHRM2DRD3 | |
| SCHEMBL4737218 | 0.82 | P2RY12 (0.58) | P2RY12CYP3A4CYP2C9CHRM2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008085119-A1 | NEW PYRIDINE ANALOGUES VIII 518 | ASTRAZENECA AB (SE) | 2008-07-17 | — | — | WO | disclosed |