Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 3/20 | 0.52 |
| ▸ | POLA1 | P09884 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | FNTA | P49354 | 2/20 | 0.49 |
| ▸ | FNTB | P49356 | 2/20 | 0.49 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.49 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.49 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.49 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.49 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.49 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.49 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.49 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4735209 | 1.00 | CDC25A (0.52) | CDC25APOLA1CYP2D6CYP2C19FNTA | |
| SCHEMBL4735194 | 0.99 | CDC25A (0.51) | CDC25APOLA1CYP2D6CYP2C19FNTA | |
| SCHEMBL4739288 | 0.99 | CDC25A (0.51) | CDC25APOLA1CYP2D6CYP2C19FNTA | |
| SCHEMBL4735707 | 0.99 | CDC25A (0.51) | CDC25APOLA1CYP2D6CYP2C19FNTA | |
| SCHEMBL4786672 | 0.99 | CDC25A (0.51) | CDC25APOLA1CYP2D6CYP2C19FNTA | |
| SCHEMBL4736747 | 0.99 | CDC25A (0.51) | CDC25APOLA1CYP2D6CYP2C19FNTA | |
| SCHEMBL4739199 | 0.99 | CDC25A (0.51) | CDC25APOLA1CYP2D6CYP2C19FNTA | |
| SCHEMBL4736136 | 0.99 | CDC25A (0.51) | CDC25APOLA1CYP2D6CYP2C19FNTA | |
| SCHEMBL4734427 | 0.99 | CDC25A (0.51) | CDC25APOLA1CYP2D6CYP2C19FNTA | |
| SCHEMBL4735768 | 0.99 | CDC25A (0.51) | CDC25APOLA1CYP2D6CYP2C19FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008077247-A1 | COATINGS FOR IMPLANTABLE MEDICAL DEVICES COMPRISING CHOLESTEROL | MIV THERAPEUTICS INC. (CA) | 2008-07-03 | — | — | WO | disclosed |