SCHEMBL4738101

SCHEMBL4738101

Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1NC(=O)OC(C)C.Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1NC(=O)OCc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FASN P49327 20/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4736514 0.94 FASN (0.58) FASN
SCHEMBL4739469 0.91 FASN (0.63) FASN
SCHEMBL4737674 0.87 FASN (0.62) FASN
SCHEMBL4735276 0.87 FASN (0.57) FASN
SCHEMBL4196871 0.86 FASN (0.57) FASN
SCHEMBL4913426 0.86 FASN (0.48) FASN
SCHEMBL4734067 0.85 FASN (0.62) FASN
SCHEMBL4734941 0.85 FASN (0.53) FASN
SCHEMBL4735386 0.85 FASN (0.52) FASN
SCHEMBL4735570 0.85 FASN (0.53) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008075077-A1 PIPERIDINE DERIVATIVES FOR THE TREATMENT OF OBESITY ASTRAZENECA AB (SE) 2008-06-26 WO claimed
WO-2008075077-A1 PIPERIDINE DERIVATIVES FOR THE TREATMENT OF OBESITY ASTRAZENECA AB (SE) 2008-06-26 WO disclosed