SCHEMBL4738174

SCHEMBL4738174

CC(=O)NCCCN(C(N)=O)c1cc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)ccc1C

nearest known ligand 0.52

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FASN P49327 20/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4207115 0.91 FASN (0.52) FASN
SCHEMBL4203527 0.90 FASN (0.49) FASN
SCHEMBL4203212 0.88 FASN (0.53) FASN
SCHEMBL4204882 0.88 FASN (0.48) FASN
SCHEMBL4203643 0.88 FASN (0.56) FASN
SCHEMBL4199547 0.88 FASN (0.53) FASN
SCHEMBL4207436 0.87 FASN (0.52) FASN
SCHEMBL4739507 0.87 FASN (0.52) FASN
SCHEMBL4199414 0.87 FASN (0.54) FASN
SCHEMBL4202879 0.86 FASN (0.55) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008075064-A1 PIPERIDINE DERIVATIVES FOR THE TREATMENT OF OBESITY ASTRAZENECA AB (SE) 2008-06-26 WO disclosed