SCHEMBL4738437

SCHEMBL4738437

C=C(c1ccccc1)c1ccc(C)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.60
CES1 P23141 2/20 0.60
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
NPC1 O15118 4/20 0.54
RAB9A P51151 4/20 0.54
LMNA P02545 3/20 0.48
POLB P06746 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
ALDH1A1 P00352 2/20 0.48
TSHR P16473 1/20 0.48
ALOX12 P18054 1/20 0.48
ACHE P22303 1/20 0.48
MAPT P10636 2/20 0.46
HTT P42858 1/20 0.46
GFER P55789 1/20 0.46
HSD17B10 Q99714 1/20 0.46
GPR55 Q9Y2T6 1/20 0.46
CYP2D6 P10635 1/20 0.45
HIF1A Q16665 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL893597 0.89 HTT (0.55) CES2CES1MEN1KMT2ANPC1
SCHEMBL4412916 0.89 HTT (0.55) CES2CES1MEN1KMT2ANPC1
SCHEMBL9806265 0.89 MEN1 (0.48) CES2CES1MEN1KMT2ANPC1
SCHEMBL22482627 0.88 MEN1 (0.48) CES2CES1MEN1KMT2ANPC1
SCHEMBL19369977 0.88 MEN1 (0.63) CES2CES1MEN1KMT2ANPC1
Diphenylamine SCHEMBL613821 0.88 HPGD (0.63) CES2CES1MEN1KMT2ANPC1
SCHEMBL894135 0.87 MEN1 (0.65) CES2CES1MEN1KMT2ALMNA
SCHEMBL610912 0.86 NPC1 (0.47) CES2CES1MEN1KMT2ANPC1
SCHEMBL2749446 0.86 MEN1 (0.45) CES2CES1MEN1KMT2ANPC1
Lithium SCHEMBL31099176 0.84 MEN1 (0.44) CES2CES1MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119462499-A 2-Fluoroalkyl quinoline derivative and synthesis method thereof 浙江禾本科技股份有限公司 2025-02-18 CN claimed
CN-118771963-A Method for realizing double-carbon functional conversion of olefin through carboxylic acid decarboxylation by using sulfur hexafluoride as oxidizing agent 国网安徽省电力有限公司电力科学研究院 2024-10-15 CN claimed
EP-1171222-B1 PROCESS FOR REMOVING HYDROGEN SULFIDE FROM GASES CRYSTATECH INC (US) 2004-09-01 EP claimed
EP-0158809-B1 ELECTRICAL INSULATING OIL AND OIL-FILLED ELECTRICAL APPLIANCES NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-01-25 EP claimed
US-4618914-A 1,1-DIARYLALKENES; HEAT RESISTANCE NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1986-10-21 US claimed
EP-0158809-A1 Electrical insulating oil and oil-filled electrical appliances NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1985-10-23 EP claimed
CN-119874468-A Novel method for introducing alkyl on nitrogen-containing heterocyclic molecule by photocatalytic C-Cl bond activation 扬州大学 2025-04-25 CN disclosed
CN-119462499-A 2-Fluoroalkyl quinoline derivative and synthesis method thereof 浙江禾本科技股份有限公司 2025-02-18 CN disclosed
CN-119118890-A Alkenyl thioester compound and preparation method thereof 吉林化工学院 2024-12-13 CN disclosed
CN-118771963-A Method for realizing double-carbon functional conversion of olefin through carboxylic acid decarboxylation by using sulfur hexafluoride as oxidizing agent 国网安徽省电力有限公司电力科学研究院 2024-10-15 CN disclosed
CN-118373738-A Method for preparing gamma-aldehyde carboxylic ester by carbon dioxide 常州大学 2024-07-23 CN disclosed
CN-114853804-B Method for synthesizing high-regioselectivity alpha-alkenyl stannane by hydrogenating terminal alkyne stannum marshi 浙江大学 2024-07-05 CN disclosed
CN-118108668-A Fluorosulphonamide reagent and preparation method and application thereof 中山大学 2024-05-31 CN disclosed
EP-0154993-B1 ELECTRICAL INSULATING OIL AND ELECTRICAL APPLIANCES IMPREGNATED WITH THE SAME NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1988-03-09 EP disclosed
US-4621302-A MONO-OR DIOLEFIN HAVING THREE CONDENSED OR NON-CONDENSED AROMATIC RINGS NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1986-11-04 US disclosed
US-4618914-A 1,1-DIARYLALKENES; HEAT RESISTANCE NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1986-10-21 US disclosed
US-4605755-A Preparation of 1,1-diphenyl-2-carboethoxycyclopropane STAUFFER CHEMICAL COMPANY (US) 1986-08-12 US disclosed
EP-0180771-A1 Method for improving impulse breakdown strength of electrically insulating materials Nippon Petrochemicals Co., Ltd. (JP) 1986-05-14 EP disclosed
EP-0158809-A1 Electrical insulating oil and oil-filled electrical appliances NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1985-10-23 EP disclosed
EP-0154993-A1 Electrical insulating oil and electrical appliances impregnated with the same NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1985-09-18 EP disclosed