⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloromethane SCHEMBL1397391 | 1.00 | — | — | |
| Chloromethane SCHEMBL12100249 | 0.91 | — | — | |
| Chloromethane SCHEMBL9950329 | 0.91 | — | — | |
| Chloromethane SCHEMBL2137478 | 0.91 | — | — | |
| Carbon Tetrachloride SCHEMBL4518046 | 0.84 | — | — | |
| Methyl Alcohol SCHEMBL27398618 | 0.80 | — | — | |
| Chloromethane SCHEMBL10458728 | 0.80 | — | — | |
| Methoxymethane SCHEMBL22804153 | 0.79 | — | — | |
| Trichloroethane SCHEMBL9551985 | 0.79 | — | — | |
| Chloroform SCHEMBL28176439 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906558-B1 | SODIUM CHANNEL BLOCKERS, PREPARATION METHOD THEREOF AND USE THEREOF | DAE WOONG PHARMA (KR) | 2020-09-02 | — | — | EP | disclosed |
| US-9376429-B2 | Sodium channel blockers, preparation method thereof and use thereof | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2016-06-28 | — | — | US | disclosed |
| US-20150336944-A1 | Sodium Channel Blockers, Preparation Method Thereof and Use Thereof | IN THERAPEUTICS (KR) | 2015-11-26 | — | — | US | disclosed |
| EP-2906558-A1 | SODIUM CHANNEL BLOCKERS, PREPARATION METHOD THEREOF AND USE THEREOF | Daewoong Pharmaceutical Co., Ltd. (KR) | 2015-08-19 | — | — | EP | disclosed |
| WO-2014061970-A1 | SODIUM CHANNEL BLOCKERS, PREPARATION METHOD THEREOF AND USE THEREOF | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2014-04-24 | — | — | WO | disclosed |
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | disclosed |