Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPOR | P19235 | 4/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5548812 | 1.00 | EPOR (0.42) | EPORANPEPF2MMP2MMP9 | |
| SCHEMBL8893033 | 0.94 | CYP1A2 (0.37) | EPORCYP1A2TSHR | |
| SCHEMBL8892535 | 0.94 | CYP1A2 (0.37) | EPORCYP1A2TSHR | |
| Trifluoroacetic Acid SCHEMBL4359902 | 0.94 | EPOR (0.38) | EPORANPEPF2MMP2MMP9 | |
| Trifluoroacetic Acid SCHEMBL4355575 | 0.91 | EPOR (0.36) | EPORANPEPF2TLR2DPP7 | |
| SCHEMBL25182246 | 0.91 | PRSS1 (0.37) | TLR2 | |
| SCHEMBL25179548 | 0.89 | CYP1A2 (0.34) | EPORCYP1A2TSHR | |
| SCHEMBL1000116 | 0.89 | BCHE (0.37) | CYP1A2TSHR | |
| SCHEMBL1000114 | 0.89 | BCHE (0.37) | CYP1A2TSHR | |
| SCHEMBL8158096 | 0.89 | BCHE (0.37) | CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008089487-A2 | CARBOXYETHYLPYRROLE COMPOUNDS AND METHODS OF THEIR PRODUCTION | THE CLEVELAND CLINIC FOUNDATION (US) | 2008-07-24 | — | — | WO | disclosed |
| WO-2008089485-A2 | CARBOXYETHYLPYRROLE COMPOUNDS AND METHODS OF THEIR PRODUCTION | THE CLEVELAND CLINIC FOUNDATION (US) | 2008-07-24 | — | — | WO | disclosed |