Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 10/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 15/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 7/20 | 0.41 |
| ▸ | OGFOD1 | Q8N543 | 1/20 | 0.41 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | USP5 | P45974 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4992312 | 0.86 | EGLN3 (0.47) | EGLN3EGLN1EGLN2OGFOD1HIF1AN | |
| SCHEMBL4737678 | 0.83 | EGLN3 (0.48) | EGLN3EGLN1EGLN2OGFOD1HIF1AN | |
| SCHEMBL4738041 | 0.75 | EGLN3 (0.49) | EGLN3EGLN1EGLN2CYSLTR2 | |
| SCHEMBL5000261 | 0.75 | EGLN3 (0.63) | EGLN3EGLN1EGLN2CYSLTR2 | |
| SCHEMBL4738691 | 0.75 | EGLN1 (0.59) | EGLN3EGLN1EGLN2CYSLTR2 | |
| SCHEMBL4992208 | 0.75 | EGLN3 (0.63) | EGLN3EGLN1EGLN2CYSLTR2 | |
| SCHEMBL4996212 | 0.74 | EGLN3 (0.64) | EGLN3EGLN1EGLN2CYSLTR2 | |
| SCHEMBL4989808 | 0.72 | EGLN1 (0.42) | EGLN3EGLN1EGLN2OGFOD1HIF1AN | |
| SCHEMBL4741309 | 0.71 | KMT2A (0.39) | KMT2A | |
| SCHEMBL4991849 | 0.70 | EGLN3 (0.51) | EGLN3EGLN1EGLN2OGFOD1HIF1AN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008089051-A1 | N-SUBSTITUTED GLYCINE DERIVATIVES: PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-07-24 | — | — | WO | claimed |