Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 20/20 | 0.65 |
| ▸ | HCRTR2 | O43614 | 20/20 | 0.65 |
| ▸ | TSPO | P30536 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1398540 | 0.93 | HCRTR1 (0.57) | HCRTR1HCRTR2 | |
| SCHEMBL4741190 | 0.90 | HCRTR1 (0.71) | HCRTR1HCRTR2 | |
| SCHEMBL1599349 | 0.89 | HCRTR1 (0.67) | HCRTR1HCRTR2 | |
| SCHEMBL1599350 | 0.89 | HCRTR1 (0.67) | HCRTR1HCRTR2 | |
| SCHEMBL16277741 | 0.89 | HCRTR1 (0.67) | HCRTR1HCRTR2 | |
| SCHEMBL15174448 | 0.89 | HCRTR1 (0.67) | HCRTR1HCRTR2 | |
| SCHEMBL16278209 | 0.89 | HCRTR1 (0.67) | HCRTR1HCRTR2 | |
| SCHEMBL16282485 | 0.89 | HCRTR1 (0.67) | HCRTR1HCRTR2 | |
| SCHEMBL15174166 | 0.89 | HCRTR1 (0.67) | HCRTR1HCRTR2 | |
| SCHEMBL4787101 | 0.88 | HCRTR1 (0.70) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087611-A2 | PYRROLIDINE- AND PIPERIDINE- BIS-AMIDE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2008-07-24 | — | — | WO | claimed |
| WO-2008087611-A2 | PYRROLIDINE- AND PIPERIDINE- BIS-AMIDE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2008-07-24 | — | — | WO | disclosed |