SCHEMBL4739352

SCHEMBL4739352

Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1CC(C)NC(N)=O

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FASN P49327 20/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4782520 0.91 FASN (0.51) FASN
SCHEMBL4739036 0.89 FASN (0.57) FASN
SCHEMBL4734651 0.85 FASN (0.52) FASN
SCHEMBL4205023 0.80 FASN (0.67) FASN
SCHEMBL4736422 0.79 FASN (0.66) FASN
SCHEMBL4168210 0.79 FASN (0.64) FASN
SCHEMBL30010047 0.79 FASN (0.64) FASN
SCHEMBL12488860 0.78 FASN (0.73) FASN
SCHEMBL4739058 0.78 FASN (0.49) FASN
SCHEMBL4193382 0.78 FASN (0.64) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008075064-A1 PIPERIDINE DERIVATIVES FOR THE TREATMENT OF OBESITY ASTRAZENECA AB (SE) 2008-06-26 WO disclosed