Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 11/20 | 0.70 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.70 |
| ▸ | NPC1 | O15118 | 2/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.70 |
| ▸ | MTOR | P42345 | 2/20 | 0.70 |
| ▸ | RAB9A | P51151 | 2/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.70 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.70 |
| ▸ | HTR2C | P28335 | 2/20 | 0.70 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.70 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4785574 | 0.93 | SLC6A4 (0.76) | SLC6A4MEN1KMT2ALMNANPC1 | |
| Oxalic Acid SCHEMBL4739531 | 0.90 | SLC6A4 (0.72) | SLC6A4MEN1KMT2ALMNANPC1 | |
| Fluoxetine SCHEMBL8722258 | 0.90 | SLC6A4 (0.88) | SLC6A4MEN1KMT2ALMNANPC1 | |
| SCHEMBL5322164 | 0.86 | SLC6A4 (0.65) | SLC6A4MEN1KMT2ALMNANPC1 | |
| Hydrochloric Acid SCHEMBL5351653 | 0.85 | SLC6A4 (0.66) | SLC6A4MEN1KMT2ALMNANPC1 | |
| Fluoxetine SCHEMBL6008121 | 0.85 | SLC6A4 (0.88) | SLC6A4MEN1KMT2ALMNANPC1 | |
| Fluoxetine SCHEMBL3242735 | 0.84 | SLC6A4 (0.86) | SLC6A4MEN1KMT2ALMNANPC1 | |
| Oxalic Acid SCHEMBL4736671 | 0.84 | SLC6A4 (0.63) | SLC6A4MEN1KMT2ALMNANPC1 | |
| Fluoxetine SCHEMBL570572 | 0.83 | SLC6A4 (1.00) | SLC6A4MEN1KMT2ALMNANPC1 | |
| Fluoxetine SCHEMBL8353 | 0.83 | SLC6A4 (1.00) | SLC6A4MEN1KMT2ALMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008081477-A1 | 3-ARYLOXY 3-SUBSTITUTED PROPANAMINES | NATCO PHARMA LIMITED (IN) | 2008-07-10 | — | — | WO | disclosed |