Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.62 |
| ▸ | CA2 | P00918 | 5/20 | 0.62 |
| ▸ | CA7 | P43166 | 5/20 | 0.62 |
| ▸ | CA9 | Q16790 | 5/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.57 |
| ▸ | PLG | P00747 | 1/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.57 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4741254 | 0.90 | CA1 (0.53) | CA1CA2CA7CA9CA14 | |
| SCHEMBL4785416 | 0.78 | KMT2A (0.59) | CA1CA2CA7CA9CA14 | |
| SCHEMBL3052857 | 0.78 | PDE4B (0.69) | CA1CA2CA7CA9CA14 | |
| SCHEMBL5125288 | 0.77 | KMT2A (0.68) | CA1CA2CA7CA9CA14 | |
| SCHEMBL8103530 | 0.76 | CA1 (0.64) | CA1CA2CA7CA9CA14 | |
| SCHEMBL16523572 | 0.76 | STS (0.59) | CA1CA2CA7CA9CA14 | |
| SCHEMBL8239825 | 0.75 | CA1 (0.72) | CA1CA2CA7CA9CA14 | |
| SCHEMBL7893969 | 0.75 | KMT2A (0.85) | CA1CA2CA7CA9CA14 | |
| SCHEMBL3056380 | 0.74 | CA1 (0.68) | CA1CA2CA7CA9CA14 | |
| SCHEMBL16523571 | 0.74 | CA1 (0.61) | CA1CA2CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008095852-A1 | BRONCHORELAXING ARYLAMIDES | RESPIRATORIUS AB (SE) | 2008-08-14 | — | — | WO | disclosed |