Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 9/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ASF1A | Q9Y294 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4226961 | 0.99 | MCHR1 (0.50) | MCHR1SMN1; SMN2NPSR1FGFR1PKM | |
| SCHEMBL4238167 | 0.96 | MCHR1 (0.52) | MCHR1SMN1; SMN2NPSR1FGFR1PKM | |
| SCHEMBL4233256 | 0.94 | MCHR1 (0.49) | MCHR1SMN1; SMN2NPSR1FGFR1PKM | |
| SCHEMBL4741625 | 0.91 | MCHR1 (0.44) | MCHR1SMN1; SMN2NPSR1FGFR1PKM | |
| SCHEMBL4236062 | 0.91 | MCHR1 (0.47) | MCHR1SMN1; SMN2NPSR1FGFR1PKM | |
| SCHEMBL4233894 | 0.91 | MCHR1 (0.47) | MCHR1SMN1; SMN2NPSR1FGFR1PKM | |
| SCHEMBL4235333 | 0.91 | SMN1; SMN2 (0.52) | MCHR1SMN1; SMN2NPSR1FGFR1PKM | |
| SCHEMBL4236975 | 0.91 | MCHR1 (0.47) | MCHR1SMN1; SMN2NPSR1FGFR1PKM | |
| SCHEMBL4232443 | 0.90 | FGFR1 (0.49) | MCHR1SMN1; SMN2NPSR1FGFR1PKM | |
| SCHEMBL4228574 | 0.90 | MCHR1 (0.46) | MCHR1SMN1; SMN2NPSR1FGFR1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |