SCHEMBL4739464

SCHEMBL4739464

Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1N(C(N)=O)[C@@H](CCS(C)(=O)=O)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FASN P49327 20/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4737320 0.89 FASN (0.52) FASN
SCHEMBL4735918 0.83 FASN (0.53) FASN
SCHEMBL4736666 0.81 FASN (0.48) FASN
SCHEMBL4739776 0.79 FASN (0.52) FASN
SCHEMBL4195156 0.79 FASN (0.54) FASN
SCHEMBL4191345 0.78 FASN (0.47) FASN
SCHEMBL4202879 0.78 FASN (0.55) FASN
SCHEMBL4199547 0.77 FASN (0.53) FASN
SCHEMBL4199028 0.77 FASN (0.56) FASN
SCHEMBL4168210 0.77 FASN (0.64) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008075064-A1 PIPERIDINE DERIVATIVES FOR THE TREATMENT OF OBESITY ASTRAZENECA AB (SE) 2008-06-26 WO disclosed