Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 18/20 | 0.49 |
| ▸ | PPARD | Q03181 | 15/20 | 0.49 |
| ▸ | PPARG | P37231 | 10/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4739674 | 1.00 | PPARA (0.49) | PPARAPPARDPPARGFFAR1TNFRSF1A | |
| SCHEMBL14146386 | 0.91 | PPARA (0.41) | PPARAPPARDPPARGFFAR1 | |
| SCHEMBL4741598 | 0.85 | CXCL12 (0.42) | PPARAPPARDPPARGFFAR1 | |
| SCHEMBL4741599 | 0.85 | CXCL12 (0.42) | PPARAPPARDPPARGFFAR1 | |
| SCHEMBL2463947 | 0.79 | MAPT (0.43) | PPARAPPARDPPARGFFAR1 | |
| SCHEMBL2464435 | 0.78 | PPARD (0.44) | PPARAPPARDPPARGFFAR1 | |
| SCHEMBL2463761 | 0.76 | PPARA (0.54) | PPARAPPARDPPARGTNFRSF1A | |
| SCHEMBL12648327 | 0.76 | PPARA (0.54) | PPARAPPARDPPARGTNFRSF1A | |
| SCHEMBL2464492 | 0.76 | PPARD (0.61) | PPARAPPARDPPARG | |
| SCHEMBL12648524 | 0.76 | PPARD (0.61) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087367-A2 | SUBSTITUTED (PHENYLTHIAZOLYL)-PHENYL-PROPAN-1-ONE AND (PHENYLOXAZODYL)-PHENYL-PROPAN-1-ONE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | claimed |
| WO-2008087367-A2 | SUBSTITUTED (PHENYLTHIAZOLYL)-PHENYL-PROPAN-1-ONE AND (PHENYLOXAZODYL)-PHENYL-PROPAN-1-ONE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |