Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4734966 | 0.88 | PARP10 (0.40) | PARP10PARP15PARP2FFAR4SCN9A | |
| SCHEMBL22657649 | 0.81 | PARP10 (0.42) | PARP10PARP15PARP2FFAR4SCN9A | |
| SCHEMBL17609427 | 0.78 | PARP10 (0.42) | PARP10PARP15PARP2FFAR4SCN9A | |
| SCHEMBL4678272 | 0.78 | PARP10 (0.46) | PARP10PARP15PARP2FFAR4SCN9A | |
| SCHEMBL12077349 | 0.78 | KAT6A (0.46) | PARP10PARP15PARP2KAT6A | |
| SCHEMBL14901056 | 0.77 | PARP10 (0.55) | PARP10PARP15PARP2FFAR4SCN9A | |
| SCHEMBL9111876 | 0.77 | PARP10 (0.41) | PARP10PARP15PARP2SCN9AKAT6A | |
| SCHEMBL21718870 | 0.77 | PARP10 (0.41) | PARP10PARP15PARP2SCN9AKAT6A | |
| SCHEMBL9111879 | 0.77 | PARP10 (0.41) | PARP10PARP15PARP2SCN9AKAT6A | |
| SCHEMBL19478658 | 0.77 | PARP10 (0.41) | PARP10PARP15PARP2FFAR4KAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343775-B1 | PIPERAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-06-04 | — | — | EP | claimed |