SCHEMBL4740412

SCHEMBL4740412

Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1N(C(N)=O)C(Cc1ccc(F)cc1)C(=O)O.Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1NC(=O)NC(C)c1ccccn1

nearest known ligand 0.46

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FASN P49327 20/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4740414 0.89 FASN (0.51) FASN
SCHEMBL4740416 0.84 FASN (0.46) FASN
SCHEMBL4200433 0.84 FASN (0.63) FASN
SCHEMBL4191345 0.80 FASN (0.47) FASN
SCHEMBL4198979 0.79 FASN (0.55) FASN
SCHEMBL14162248 0.77 FASN (0.53) FASN
SCHEMBL4189217 0.77 FASN (0.61) FASN
SCHEMBL4737320 0.75 FASN (0.52) FASN
SCHEMBL4196120 0.75 FASN (0.62) FASN
SCHEMBL4201015 0.75 FASN (0.62) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008075064-A1 PIPERIDINE DERIVATIVES FOR THE TREATMENT OF OBESITY ASTRAZENECA AB (SE) 2008-06-26 WO disclosed