Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 3/20 | 0.41 |
| ▸ | ABAT | P80404 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.30 |
| ▸ | BLM | P54132 | 2/20 | 0.30 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2875707 | 0.83 | CYP2C9 (0.32) | GABRR1CYP2C9PARP1PARP15PARP10 | |
| SCHEMBL358241 | 0.80 | GRIK1 (0.34) | CYP2C9 | |
| SCHEMBL22214 | 0.79 | — | — | |
| SCHEMBL17438080 | 0.79 | — | — | |
| SCHEMBL8743386 | 0.77 | CYP2C9 (0.33) | CYP2C9 | |
| SCHEMBL10875230 | 0.77 | GRIK1 (0.38) | CYP2C9 | |
| Hydrochloric Acid SCHEMBL28458261 | 0.77 | — | — | |
| SCHEMBL4557382 | 0.75 | CYP2C9 (0.35) | CYP2C9PARP1PARP15PARP10 | |
| SCHEMBL19967947 | 0.75 | GABRR1 (0.39) | GABRR1ABAT | |
| SCHEMBL20472371 | 0.74 | GABRR1 (0.41) | GABRR1ABATGABRR2BLMGABRR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008085119-A1 | NEW PYRIDINE ANALOGUES VIII 518 | ASTRAZENECA AB (SE) | 2008-07-17 | — | — | WO | disclosed |