Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8493911 | 0.87 | PPARG (0.44) | CYP1A2CYP2C19CYP2C9LMNAHTT | |
| SCHEMBL29738633 | 0.83 | CYP1A2 (0.53) | CYP1A2CYP2C19CYP2C9LMNAHTT | |
| SCHEMBL5978737 | 0.80 | CYP1A2 (0.44) | CYP1A2CYP2C19CYP2C9LMNAHTT | |
| SCHEMBL9626674 | 0.80 | CYP1A2 (0.44) | CYP1A2CYP2C19CYP2C9LMNAHTT | |
| SCHEMBL425182 | 0.80 | SMN1; SMN2 (0.50) | CYP1A2CYP2C19CYP2C9LMNAHTT | |
| SCHEMBL6042549 | 0.79 | CYP2C19 (0.52) | CYP1A2CYP2C19CYP2C9LMNAHTT | |
| SCHEMBL3674399 | 0.78 | CYP1A2 (0.63) | CYP1A2CYP2C19CYP2C9LMNACYP2D6 | |
| SCHEMBL20378831 | 0.77 | HPGD (0.46) | CYP1A2CYP2C19CYP2C9LMNAHTT | |
| SCHEMBL25316972 | 0.76 | IDO1 (0.46) | ALDH1A1CYP3A4IDO1MAPTALOX12 | |
| SCHEMBL5167569 | 0.76 | IDO1 (0.46) | ALDH1A1IDO1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096128-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES 2 | ARGENTA DISCOVERY LTD (GB) | 2008-08-14 | — | — | WO | disclosed |
| WO-2008096128-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES 2 | ARGENTA DISCOVERY LTD (GB) | 2008-08-14 | — | — | WO | disclosed |