Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ceronapril SCHEMBL1649023 | 1.00 | ACE (1.00) | ACE | |
| Ceronapril SCHEMBL121163 | 1.00 | ACE (1.00) | ACE | |
| Ceronapril SCHEMBL121164 | 1.00 | ACE (1.00) | ACE | |
| SCHEMBL9353704 | 0.99 | ACE (0.98) | ACE | |
| Ceronapril SCHEMBL387939 | 0.99 | ACE (0.98) | ACE | |
| SCHEMBL9353553 | 0.99 | ACE (0.98) | ACE | |
| Ceronapril SCHEMBL387940 | 0.99 | ACE (0.98) | ACE | |
| SCHEMBL9353210 | 0.97 | ACE (0.95) | ACE | |
| SCHEMBL9353217 | 0.97 | ACE (0.95) | ACE | |
| SCHEMBL10430204 | 0.95 | ACE (0.91) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 268 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5212165-A | Enzyme inhibitor | E. R. SQUIBB & SONS, INC. (US) | 1993-05-18 | — | — | US | claimed |
| EP-0481207-A1 | Method for preventing or inhibiting loss of cognitive function employing a combination of an ace inhibitor and a drug that acts at serotonin receptors | E.R. SQUIBB & SONS, INC. (US) | 1992-04-22 | — | — | EP | claimed |
| EP-0477624-A1 | Method for preventing or treating depression employing a combination of an ace inhibitor and a drug that acts at serotonin receptors | E.R. SQUIBB & SONS, INC. (US) | 1992-04-01 | — | — | EP | claimed |
| US-5098889-A | Cognition activators, angiotensin converting enzyme inhibitors | E. R. SQUIBB & SONS, INC. (US) | 1992-03-24 | — | — | US | claimed |
| US-5093129-A | Angiotensin converting enzyme inhibitor | E. R. SQUIBB & SONS, INC. (US) | 1992-03-03 | — | — | US | claimed |
| US-5061694-A | METHOD FOR STABILIZING OR CAUSING REGRESSION OF ATHEROSCLEROSIS IN CORONARY ARTERIES EMPLOYING AN ACE INHIBITOR | E. R. SQUIBB & SONS, INC. (US) | 1991-10-29 | — | — | US | claimed |
| US-5037821-A | Method for inhibiting loss of cognitive functions employing a calcium channel blocker alone or in combination with an ACE inhibitor | E. R. SQUIBB & SONS, INC. (US) | 1991-08-06 | — | — | US | claimed |
| EP-0425956-A2 | ACE inhibitors for use for stabilizing or causing regression of atherosclerosis in coronary arteries | E.R. SQUIBB & SONS, INC. (US) | 1991-05-08 | — | — | EP | claimed |
| EP-0425909-A2 | Method for rehabilitating the vasorelaxant action of the coronary arteries impaired through atherosclerosis or hypercholesterolemia employing an ace inhibitor | E.R. SQUIBB & SONS, INC. (US) | 1991-05-08 | — | — | EP | claimed |
| EP-0418582-A2 | Method for treating hypermotility diseases of the bowel employing an ace inhibitor | E.R. SQUIBB & SONS, INC. (US) | 1991-03-27 | — | — | EP | claimed |
| US-4962095-A | Method of reducing pre-and post-ischemic myocardial arrhythmias and fibrillation | E. R. SQUIBB & SONS, INC. (US) | 1990-10-09 | — | — | US | claimed |
| EP-0383258-A2 | Pharmaceutical compositions for reducing pre and post-ischemic myocardial arrhythmias and fibrillation | E.R. SQUIBB & SONS, INC. (US) | 1990-08-22 | — | — | EP | claimed |
| US-4931430-A | Method for preventing or treating anxiety employing an ACE inhibitor | E. R. SQUIBB & SONS, INC. (US) | 1990-06-05 | — | — | US | claimed |
| EP-0229520-B1 | ORALLY ACTIVE PHOSPHONYL HYDROXYACYL PROLINES AND PROCESSES FOR PREPARING PHOSPHONYL HYDROXYACYL PROLINES | E.R. Squibb & Sons, Inc. (US) | 1990-05-30 | — | — | EP | claimed |
| US-4912096-A | Such as 1-(6-amino-2-((hydroxy(4-phenylbutyl)phosphinyl)oxy 1-oxohexyl)proline, fosinopril or zofenopril | E. R. SQUIBB & SONS, INC. (US) | 1990-03-27 | — | — | US | claimed |
| EP-0344995-A2 | Method for inhibiting loss of cognitive functions employing a calcium channel blocker alone or in combination with an ace inhibitor | E.R. SQUIBB & SONS, INC. (US) | 1989-12-06 | — | — | EP | claimed |
| EP-0334264-A2 | Pharmaceutical compositions for treating tardive dyskinesia employing an ace inhibitor | E.R. Squibb & Sons, Inc. (US) | 1989-09-27 | — | — | EP | claimed |
| EP-0321221-A2 | Method for preventing or treating anxiety employing an ace inhibitor | E.R. Squibb & Sons, Inc. (US) | 1989-06-21 | — | — | EP | claimed |
| EP-0288907-A2 | Method for inhibiting loss of cognitive functions employing an ACE inhibitor | E.R. Squibb & Sons, Inc. (US) | 1988-11-02 | — | — | EP | claimed |
| US-4745196-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1988-05-17 | — | — | US | claimed |