Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8167897 | 1.00 | CYP2D6 (0.52) | CYP2D6KCNH2MEN1KMT2AEPHX2 | |
| SCHEMBL4741308 | 0.90 | EPHX2 (0.51) | MEN1KMT2AEPHX2 | |
| SCHEMBL4741313 | 0.90 | EPHX2 (0.51) | MEN1KMT2AEPHX2 | |
| SCHEMBL4742684 | 0.86 | CYP2D6 (0.60) | CYP2D6KCNH2 | |
| SCHEMBL4740793 | 0.86 | CYP2D6 (0.55) | CYP2D6KCNH2 | |
| SCHEMBL9934748 | 0.85 | CYP2D6 (0.55) | CYP2D6KCNH2 | |
| SCHEMBL4739490 | 0.85 | CYP2D6 (0.55) | CYP2D6KCNH2 | |
| SCHEMBL9934690 | 0.85 | CYP2D6 (0.58) | CYP2D6KCNH2 | |
| SCHEMBL9932937 | 0.84 | CYP2D6 (0.68) | CYP2D6KCNH2 | |
| SCHEMBL4739408 | 0.84 | CYP2D6 (0.68) | CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008094592-A1 | HYDROXAMIC ACID DERIVATIVES OF ANILINE USEFUL AS THERAPEUTIC AGENTS FOR TREATING ANTHRAX POISONING | PANTHERA BIOPHARNA, LLC (US) | 2008-08-07 | — | — | WO | disclosed |