Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 20/20 | 0.55 |
| ▸ | RPS6KB1 | P23443 | 5/20 | 0.51 |
| ▸ | AKT1 | P31749 | 5/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743675 | 0.81 | PDPK1 (0.57) | PDPK1RPS6KB1AKT1 | |
| SCHEMBL4741944 | 0.78 | PDPK1 (0.56) | PDPK1RPS6KB1AKT1 | |
| SCHEMBL4744982 | 0.76 | PDPK1 (0.62) | PDPK1RPS6KB1AKT1 | |
| SCHEMBL4741974 | 0.76 | PDPK1 (0.57) | PDPK1RPS6KB1AKT1 | |
| SCHEMBL4741781 | 0.74 | PDPK1 (0.47) | PDPK1RPS6KB1AKT1 | |
| SCHEMBL4741971 | 0.73 | PDPK1 (0.64) | PDPK1RPS6KB1AKT1 | |
| SCHEMBL4898760 | 0.73 | PDPK1 (0.67) | PDPK1RPS6KB1AKT1 | |
| SCHEMBL4899321 | 0.73 | PDPK1 (0.64) | PDPK1RPS6KB1AKT1 | |
| SCHEMBL4744398 | 0.73 | PDPK1 (0.56) | PDPK1RPS6KB1AKT1 | |
| SCHEMBL4744915 | 0.72 | PDPK1 (0.49) | PDPK1RPS6KB1AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008109613-A1 | BENZO[C][2,7]NAPHTHYRIDINE DERIVATIVES, AND THEIR USE AS KINASE INHIBITORS | WYETH (US) | 2008-09-12 | — | — | WO | disclosed |