Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 19/20 | 0.68 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4880271 | 1.00 | GPBAR1 (0.68) | GPBAR1PDGFRBPDGFRA | |
| SCHEMBL4878289 | 1.00 | GPBAR1 (0.68) | GPBAR1PDGFRBPDGFRA | |
| SCHEMBL4878795 | 0.87 | GPBAR1 (0.67) | GPBAR1 | |
| SCHEMBL4876524 | 0.87 | GPBAR1 (0.67) | GPBAR1 | |
| SCHEMBL4876511 | 0.87 | GPBAR1 (0.67) | GPBAR1 | |
| SCHEMBL14065464 | 0.87 | GPBAR1 (0.71) | GPBAR1 | |
| SCHEMBL4876578 | 0.87 | GPBAR1 (0.71) | GPBAR1 | |
| SCHEMBL4742085 | 0.81 | GPBAR1 (1.00) | GPBAR1 | |
| SCHEMBL4878290 | 0.79 | GPBAR1 (0.55) | GPBAR1PDGFRBPDGFRA | |
| SCHEMBL4785431 | 0.78 | GPBAR1 (0.88) | GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008097976-A1 | HETEROCYCLIC MODULATORS OF TGR5 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2008-08-14 | — | — | WO | disclosed |