Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.62 |
| ▸ | KMO | O15229 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.53 |
| ▸ | TNKS | O95271 | 1/20 | 0.51 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.51 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.51 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4256156 | 0.89 | EPHX2 (0.61) | AKR1C3NPC1POLBCYP2C9RAB9A | |
| SCHEMBL5552784 | 0.89 | AKR1C3 (0.67) | AKR1C3NPC1POLBCYP2C9RAB9A | |
| SCHEMBL1636273 | 0.88 | AKR1C3 (0.66) | AKR1C3NPC1POLBCYP2C9RAB9A | |
| SCHEMBL30241132 | 0.88 | AKR1C3 (0.66) | AKR1C3NPC1POLBCYP2C9RAB9A | |
| SCHEMBL30266789 | 0.87 | AKR1C3 (0.92) | AKR1C3NPC1POLBCYP2C9RAB9A | |
| SCHEMBL1042631 | 0.87 | AKR1C3 (0.92) | AKR1C3NPC1POLBCYP2C9RAB9A | |
| SCHEMBL16429183 | 0.85 | AKR1C3 (0.62) | AKR1C3NPC1POLBCYP2C9RAB9A | |
| SCHEMBL3507467 | 0.85 | MRGPRX4 (0.60) | AKR1C3NPC1POLBCYP2C9RAB9A | |
| SCHEMBL4320685 | 0.85 | AKR1C3 (0.96) | AKR1C3NPC1POLBCYP2C9RAB9A | |
| SCHEMBL29546656 | 0.85 | AKR1C3 (0.96) | AKR1C3NPC1POLBCYP2C9RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |
| WO-2008090357-A2 | N, N; -SUBSTITUTED PIPERAZINES BINDING TO MELANOCORTIN RECEPTOR | PALATIN TECHNOLOGIES, INC. (US) | 2008-07-31 | — | — | WO | disclosed |
| US-4778914-A | FOR HALOGENATED DIPHENYL ETHER HERBICIDE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-10-18 | — | — | US | disclosed |
| US-4388472-A | Substituted diphenyl ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-06-14 | — | — | US | disclosed |
| EP-0023100-B1 | HERBICIDAL COMPOSITIONS COMPRISING A DIPHENYL ETHER COMPOUND IN ADMIXTURE WITH ANOTHER HERBICIDE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-11-10 | — | — | EP | disclosed |
| EP-0003416-B1 | DIPHENYL ETHER COMPOUNDS USEFUL AS HERBICIDES; METHODS OF USING THEM, PROCESSES FOR PREPARING THEM, AND HERBICIDAL COMPOSITIONS CONTAINING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-08-26 | — | — | EP | disclosed |
| US-4285723-A | DERIVATIVES OF 3-PHENOXY-SULFONYLBENZAMIDE; NONPHYTOTOXIC PRE- AND POSTEMERGENCE HERBICIDES; CROPS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-08-25 | — | — | US | disclosed |
| EP-0023100-A1 | Herbicidal compositions comprising a diphenyl ether compound in admixture with another herbicide | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-01-28 | — | — | EP | disclosed |
| EP-0003416-A1 | Diphenyl ether compounds useful as herbicides; methods of using them, processes for preparing them, and herbicidal compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-08-08 | — | — | EP | disclosed |