Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.69 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.69 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.39 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17532656 | 0.98 | ESR1 (0.68) | ESR1ESR2ACHEALDH1A1L3MBTL1 | |
| SCHEMBL5524287 | 0.92 | ESR1 (0.74) | ESR1ESR2ACHEALDH1A1L3MBTL1 | |
| SCHEMBL1257469 | 0.91 | ESR1 (0.59) | ESR1ESR2ACHEALDH1A1L3MBTL1 | |
| SCHEMBL12893182 | 0.91 | ESR1 (0.59) | ESR1ESR2ACHEALDH1A1L3MBTL1 | |
| SCHEMBL12893282 | 0.89 | ESR1 (0.67) | ESR1ESR2ACHEALDH1A1L3MBTL1 | |
| SCHEMBL1257862 | 0.89 | ESR1 (0.57) | ESR1ESR2ACHEALDH1A1L3MBTL1 | |
| SCHEMBL15308825 | 0.82 | ESR1 (0.58) | ESR1ESR2ACHEALDH1A1L3MBTL1 | |
| SCHEMBL10776828 | 0.82 | ESR1 (1.00) | ESR1ESR2ACHEALDH1A1L3MBTL1 | |
| SCHEMBL673904 | 0.82 | ESR1 (1.00) | ESR1ESR2ACHEALDH1A1L3MBTL1 | |
| SCHEMBL297456 | 0.82 | ESR1 (0.62) | ESR1ESR2ACHEALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1751097-A1 | SUBSTITUTED N-ARYL BENZAMIDES AND RELATED COMPOUNDS FOR TREATMENT OF AMYLOID DISEASES AND SYNUCLEINOPATHIES | Proteotech, Inc. (US) | 2007-02-14 | — | — | EP | claimed |
| WO-2005113489-A1 | SUBSTITUTED N-ARYL BENZAMIDES AND RELATED COMPOUNDS FOR TREATMENT OF AMYLOID DISEASES AND SYNUCLEINOPATHIES | PROTEOTECH, INC. (US) | 2005-12-01 | — | — | WO | claimed |
| US-10996575-B2 | Electrophotographic photosensitive member, process cartridge, and image forming apparatus | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2021-05-04 | — | — | US | disclosed |
| US-20200233324-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2020-07-23 | — | — | US | disclosed |
| WO-2008097692-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATORY DISEASES | PROTEOTECH INC. (US) | 2008-08-14 | — | — | WO | disclosed |
| EP-1751097-A1 | SUBSTITUTED N-ARYL BENZAMIDES AND RELATED COMPOUNDS FOR TREATMENT OF AMYLOID DISEASES AND SYNUCLEINOPATHIES | Proteotech, Inc. (US) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005113489-A1 | SUBSTITUTED N-ARYL BENZAMIDES AND RELATED COMPOUNDS FOR TREATMENT OF AMYLOID DISEASES AND SYNUCLEINOPATHIES | PROTEOTECH, INC. (US) | 2005-12-01 | — | — | WO | disclosed |
| JP-2003089668-A | BIS(3,4-DIHYDROXYPHENYL)CYCLOHEXANE DERIVATIVE AND METHOD FOR PRODUCING THE SAME | MITSUI CHEMICALS INC | 2003-03-28 | — | — | JP | disclosed |