Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 8/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 8/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.37 |
| ▸ | MLNR | O43193 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL524278 | 1.00 | KCNH2 (0.39) | KCNH2CHRM2CHRM1SLC6A3CYP19A1 | |
| SCHEMBL523702 | 1.00 | KCNH2 (0.39) | KCNH2CHRM2CHRM1SLC6A3CYP19A1 | |
| SCHEMBL523703 | 1.00 | KCNH2 (0.39) | KCNH2CHRM2CHRM1SLC6A3CYP19A1 | |
| SCHEMBL4743353 | 1.00 | KCNH2 (0.39) | KCNH2CHRM2CHRM1SLC6A3CYP19A1 | |
| Bromide SCHEMBL524879 | 0.99 | KCNH2 (0.38) | KCNH2CHRM2CHRM1SLC6A3CYP19A1 | |
| Bromide SCHEMBL524878 | 0.99 | KCNH2 (0.38) | KCNH2CHRM2CHRM1SLC6A3CYP19A1 | |
| Bromide SCHEMBL1109805 | 0.99 | KCNH2 (0.38) | KCNH2CHRM2CHRM1SLC6A3CYP19A1 | |
| SCHEMBL13329509 | 0.99 | KCNH2 (0.39) | KCNH2CHRM2CHRM1SLC6A3CYP19A1 | |
| SCHEMBL13329512 | 0.99 | KCNH2 (0.39) | KCNH2CHRM2CHRM1SLC6A3CYP19A1 | |
| SCHEMBL1109843 | 0.99 | KCNH2 (0.39) | KCNH2CHRM2CHRM1SLC6A3CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | claimed |
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | disclosed |
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | disclosed |