Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ENPEP | Q07075 | 4/20 | 0.32 |
| ▸ | ANPEP | P15144 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19511523 | 0.98 | PTGS1 (0.44) | PTGS1SLC7A11TSHRHSD17B10ENPEP | |
| SCHEMBL7927272 | 0.86 | PTGS1 (0.46) | PTGS1SLC7A11ENPEPANPEP | |
| SCHEMBL9763734 | 0.86 | PTGS1 (0.46) | PTGS1SLC7A11TSHRHSD17B10ENPEP | |
| SCHEMBL2873837 | 0.86 | PTGS1 (0.46) | PTGS1SLC7A11ENPEPANPEP | |
| SCHEMBL1964879 | 0.85 | PTGS1 (0.55) | PTGS1SLC7A11ENPEPANPEP | |
| SCHEMBL20657045 | 0.85 | PTGS1 (0.55) | PTGS1SLC7A11ENPEPANPEP | |
| SCHEMBL5688404 | 0.84 | PTGS1 (0.44) | PTGS1SLC7A11TSHRHSD17B10ENPEP | |
| SCHEMBL361160 | 0.84 | PTGS1 (0.44) | PTGS1SLC7A11ENPEPANPEP | |
| SCHEMBL8601950 | 0.84 | TSHR (0.36) | PTGS1SLC7A11TSHRHSD17B10 | |
| SCHEMBL5149928 | 0.84 | PTGS1 (0.44) | PTGS1SLC7A11ENPEPANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020155081-A1 | Use of tris(hydroxymethyl) aminomethane in cold permanent waving processes | PROCTER & GAMBLE COMPANY, THE | 2002-10-24 | — | — | US | claimed |
| US-6426065-B1 | MIXTURE CONTAINING REDUCING AGENT | CLAIROL INCORPORATED | 2002-07-30 | — | — | US | claimed |
| WO-2002038114-A1 | USE OF TRIS(HYDROXYMETHYL)AMINOMETHANE IN COLD PERMANENT WAVING PROCESSES | P&G-CLAIROL, INC. (US) | 2002-05-16 | — | — | WO | claimed |
| US-5776962-A | Lactone compounds for treating patient with precancerous lesions | CELL PATHWAYS, INC. (US) | 1998-07-07 | — | — | US | claimed |
| WO-2008092841-A1 | METHOD OF DETECTING PREVIOUS STRAIGHTENING BY THE ACTION OF AN ALKALINE AGENT | L'OREAL (FR) | 2008-08-07 | — | — | WO | disclosed |
| EP-1033953-B1 | METHOD OF CROSS-LINKING KERATIN-BASED FILMS, SHEETS, AND BULK MATERIALS | KERAPLAST TECH LTD (US) | 2008-03-26 | — | — | EP | disclosed |
| EP-1033953-A4 | METHOD OF CROSS-LINKING KERATIN-BASED FILMS, SHEETS, AND BULK MATERIALS | KERAPLAST TECH LTD (US) | 2004-12-29 | — | — | EP | disclosed |
| US-20030035820-A1 | Keratin containing implant material | SOUTHWEST RESEARCH INSTITUTE AND KERAPLAST TECHNOLOGIES, LTD. | 2003-02-20 | — | — | US | disclosed |
| US-20020155081-A1 | Use of tris(hydroxymethyl) aminomethane in cold permanent waving processes | PROCTER & GAMBLE COMPANY, THE | 2002-10-24 | — | — | US | disclosed |
| US-6432435-B1 | Keratin-based tissue engineering scaffold | KERAPLAST TECHNOLOGIES, LTD. | 2002-08-13 | — | — | US | disclosed |
| US-6426065-B1 | MIXTURE CONTAINING REDUCING AGENT | CLAIROL INCORPORATED | 2002-07-30 | — | — | US | disclosed |
| WO-2002038114-A1 | USE OF TRIS(HYDROXYMETHYL)AMINOMETHANE IN COLD PERMANENT WAVING PROCESSES | P&G-CLAIROL, INC. (US) | 2002-05-16 | — | — | WO | disclosed |
| US-6159495-A | Porous and bulk keratin bio-polymers | KERAPLAST TECHNOLOGIES, LTD. (US) | 2000-12-12 | — | — | US | disclosed |
| US-6124265-A | Method of making and cross-linking keratin-based films and sheets | KERAPLAST TECHNOLOGIES, LTD. (US) | 2000-09-26 | — | — | US | disclosed |
| EP-1033953-A1 | METHOD OF CROSS-LINKING KERATIN-BASED FILMS, SHEETS, AND BULK MATERIALS | Keraplast Technologies Ltd. (US) | 2000-09-13 | — | — | EP | disclosed |
| US-6110487-A | Method of making porous keratin scaffolds and products of same | KERAPLAST TECHNOLOGIES LTD. (US) | 2000-08-29 | — | — | US | disclosed |
| WO-1999026570-A1 | METHOD OF CROSS-LINKING KERATIN-BASED FILMS, SHEETS, AND BULK MATERIALS | KERAPLAST TECHNOLOGIES, LTD. (US) | 1999-06-03 | — | — | WO | disclosed |
| EP-0460921-B1 | Large intestinal dissociative hard capsules | AICELLO CHEMICAL CO (JP) | 1995-03-01 | — | — | EP | disclosed |
| US-5283064-A | The wall is made of chitosans and coated with soluble polymer; | AICELLO CHEMICAL CO., LTD. (JP) | 1994-02-01 | — | — | US | disclosed |
| EP-0460921-A2 | Large intestinal dissociative hard capsules | AICELLO CHEMICAL COMPANY LIMITED (JP) | 1991-12-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020155081-A1 | Use of tris(hydroxymethyl) aminomethane in cold permanent waving processes | MGMT, TET1, TET3 | PTGS1 398/4885SLC7A11 2609/4885TSHR 2864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.