Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 11/20 | 0.64 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | PIM1 | P11309 | 3/20 | 0.53 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | RXRA | P19793 | 1/20 | 0.52 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | IGF1R | P08069 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743932 | 1.00 | HPGD (0.64) | HPGDCISD1POLBPPARGPIM1 | |
| SCHEMBL29668090 | 0.92 | HPGD (0.74) | HPGDCISD1PPARGPIM1PIM2 | |
| SCHEMBL2002770 | 0.92 | HPGD (0.74) | HPGDCISD1PPARGPIM1PIM2 | |
| SCHEMBL1162295 | 0.92 | HPGD (0.74) | HPGDCISD1PPARGPIM1PIM2 | |
| SCHEMBL2002766 | 0.92 | HPGD (0.74) | HPGDCISD1PPARGPIM1PIM2 | |
| Hydrochloric Acid SCHEMBL5169138 | 0.91 | HPGD (0.72) | HPGDCISD1PPARGPIM1PIM2 | |
| Hydrochloric Acid SCHEMBL5169128 | 0.90 | HPGD (0.71) | HPGDCISD1PPARGPIM1PIM2 | |
| SCHEMBL2002768 | 0.81 | HPGD (0.59) | HPGDCISD1PPARGPIM1PIM2 | |
| SCHEMBL12685642 | 0.80 | PIM1 (0.71) | HPGDCISD1POLBPIM1PIM2 | |
| Hydrochloric Acid SCHEMBL5169131 | 0.80 | PPARG (0.59) | HPGDCISD1PPARGPIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008075380-A2 | PROCESS FOR THE PREPARATION OF THIAZOLIDINE DERIVATIVES | IND-SWIFT LABORATORIES LIMITED (IN) | 2008-06-26 | — | — | WO | claimed |
| WO-2008105326-A1 | PROCESS FOR PRODUCTION OF 2-IMINO-4-THIAZOLIDINONE DERIVATIVE AND 2,4-THIAZOLIDINEDIONE DERIVATIVE | OHARA CHEMICAL INDUSTRIES, LTD. (JP) | 2008-09-04 | — | — | WO | disclosed |
| WO-2008075380-A2 | PROCESS FOR THE PREPARATION OF THIAZOLIDINE DERIVATIVES | IND-SWIFT LABORATORIES LIMITED (IN) | 2008-06-26 | — | — | WO | disclosed |