Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4742036 | 0.85 | F10 (0.50) | F10 | |
| SCHEMBL4744597 | 0.83 | F10 (0.49) | F10 | |
| SCHEMBL4744903 | 0.82 | F10 (0.49) | F10 | |
| SCHEMBL4687766 | 0.82 | F10 (0.40) | F10 | |
| SCHEMBL4691171 | 0.82 | NPC1 (0.46) | F10 | |
| SCHEMBL4687839 | 0.80 | F10 (0.46) | F10 | |
| SCHEMBL4690416 | 0.79 | F10 (0.49) | F10 | |
| SCHEMBL4748457 | 0.77 | F10 (0.50) | F10 | |
| SCHEMBL4807937 | 0.76 | F10 (0.54) | F10 | |
| SCHEMBL4743952 | 0.76 | F10 (0.54) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603572-A4 | LACTAM-CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2008-06-25 | — | — | EP | disclosed |
| EP-1603572-A1 | LACTAM-CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS | Bristol-Myers Squibb Company (US) | 2005-12-14 | — | — | EP | disclosed |
| WO-2004082687-A1 | LACTAM-CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-09-30 | — | — | WO | disclosed |