Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 13/20 | 0.51 |
| ▸ | PPARA | Q07869 | 13/20 | 0.51 |
| ▸ | PPARD | Q03181 | 3/20 | 0.51 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4744569 | 1.00 | KDM4E (0.52) | KDM4EKMT2APPARGPPARAPPARD | |
| SCHEMBL4747769 | 0.98 | KDM4E (0.52) | KDM4EKMT2APPARGPPARAPPARD | |
| SCHEMBL4746680 | 0.98 | KDM4E (0.52) | KDM4EKMT2APPARGPPARAPPARD | |
| SCHEMBL4744440 | 0.93 | CD274 (0.55) | KDM4EKMT2APPARGPPARACD274 | |
| SCHEMBL4744560 | 0.93 | CD274 (0.55) | KDM4EKMT2APPARGPPARACD274 | |
| SCHEMBL4746216 | 0.92 | POLB (0.57) | KDM4EKMT2APPARGPPARAPPARD | |
| SCHEMBL4787444 | 0.91 | PPARG (0.57) | KDM4EKMT2APPARGPPARAPPARD | |
| SCHEMBL4744454 | 0.91 | PPARG (0.57) | KDM4EKMT2APPARGPPARAPPARD | |
| SCHEMBL4744732 | 0.91 | KDM4E (0.53) | KDM4EKMT2APPARGPPARAPPARD | |
| SCHEMBL4743960 | 0.91 | KDM4E (0.53) | KDM4EKMT2APPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | claimed |
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |