Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.56 |
| ▸ | PPARA | Q07869 | 16/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4744152 | 0.88 | PPARG (0.55) | PPARGPPARAPPARD | |
| SCHEMBL4396618 | 0.86 | PPARG (0.62) | PPARGPPARA | |
| SCHEMBL4744513 | 0.83 | KDR (0.66) | PPARGPPARAKDR | |
| SCHEMBL6157414 | 0.79 | KDR (0.67) | PPARGPPARAMAOAMAOBKDR | |
| SCHEMBL4748511 | 0.77 | PPARG (0.54) | PPARGPPARAPPARD | |
| SCHEMBL14258669 | 0.76 | PPARG (0.79) | PPARGPPARA | |
| SCHEMBL12601812 | 0.75 | PPARG (0.79) | PPARGPPARA | |
| SCHEMBL7152950 | 0.75 | PPARA (0.50) | PPARGPPARAMAOAMAOB | |
| SCHEMBL4746588 | 0.75 | PPARG (0.61) | PPARGPPARAPPARD | |
| SCHEMBL9910242 | 0.74 | PPARG (0.70) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |