Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.54 |
| ▸ | PPARA | Q07869 | 14/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4744673 | 1.00 | PPARG (0.54) | PPARGPPARAKDM4EALDH1A1 | |
| SCHEMBL4788193 | 0.95 | PPARG (0.52) | PPARGPPARAKDM4EALDH1A1 | |
| SCHEMBL4788199 | 0.95 | PPARG (0.52) | PPARGPPARAKDM4EALDH1A1 | |
| SCHEMBL4748206 | 0.94 | KDM4E (0.54) | PPARGPPARAKDM4EALDH1A1 | |
| SCHEMBL4748204 | 0.94 | KDM4E (0.54) | PPARGPPARAKDM4EALDH1A1 | |
| SCHEMBL4747044 | 0.93 | PPARG (0.50) | PPARGPPARAKDM4EALDH1A1 | |
| SCHEMBL4747043 | 0.93 | PPARG (0.50) | PPARGPPARAKDM4EALDH1A1 | |
| SCHEMBL4747359 | 0.92 | PPARG (0.57) | PPARGPPARA | |
| SCHEMBL4744011 | 0.92 | PPARG (0.57) | PPARGPPARA | |
| SCHEMBL4746609 | 0.91 | PPARG (0.56) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |