Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743960 | 1.00 | KDM4E (0.53) | KDM4EKMT2ACD274POLBPPARA | |
| SCHEMBL4744732 | 1.00 | KDM4E (0.53) | KDM4EKMT2ACD274POLBPPARA | |
| SCHEMBL4744440 | 0.98 | CD274 (0.55) | KDM4EKMT2ACD274POLBPPARA | |
| SCHEMBL4744560 | 0.98 | CD274 (0.55) | KDM4EKMT2ACD274POLBPPARA | |
| SCHEMBL4746680 | 0.93 | KDM4E (0.52) | KDM4EKMT2ACD274PPARAALDH1A1 | |
| SCHEMBL4747769 | 0.93 | KDM4E (0.52) | KDM4EKMT2ACD274PPARAALDH1A1 | |
| SCHEMBL4748561 | 0.92 | KDM4E (0.54) | KDM4EKMT2ACD274POLBPPARA | |
| SCHEMBL4743889 | 0.92 | KDM4E (0.54) | KDM4EKMT2ACD274POLBPPARA | |
| SCHEMBL4743885 | 0.92 | KDM4E (0.54) | KDM4EKMT2ACD274POLBPPARA | |
| SCHEMBL4743654 | 0.91 | PPARA (0.57) | KDM4EKMT2ACD274POLBPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | claimed |
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |