Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 16/20 | 0.52 |
| ▸ | PPARA | Q07869 | 16/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4744825 | 1.00 | POLB (0.53) | POLBPPARGPPARACYP2C9KCNH2 | |
| Methane SCHEMBL4788111 | 0.97 | POLB (0.53) | POLBPPARGPPARACYP2C9KCNH2 | |
| SCHEMBL4744657 | 0.95 | PPARG (0.53) | PPARGPPARACYP2C9KCNH2KDR | |
| SCHEMBL4744656 | 0.95 | PPARG (0.53) | PPARGPPARACYP2C9KCNH2KDR | |
| SCHEMBL4746276 | 0.94 | KDR (0.57) | POLBPPARGPPARACYP2C9KCNH2 | |
| SCHEMBL4746275 | 0.94 | KDR (0.57) | POLBPPARGPPARACYP2C9KCNH2 | |
| SCHEMBL4747378 | 0.94 | KDR (0.58) | POLBPPARGPPARAKDRMAPT | |
| SCHEMBL4747374 | 0.94 | KDR (0.58) | POLBPPARGPPARAKDRMAPT | |
| SCHEMBL4748578 | 0.94 | KDR (0.58) | POLBPPARGPPARAKDRMAPT | |
| SCHEMBL4747305 | 0.92 | POLB (0.59) | POLBPPARGPPARAKDRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |