Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12638436 | 0.77 | CA12 (0.48) | CYP2D6 | |
| SCHEMBL9148991 | 0.76 | CYP2D6 (0.50) | CYP2D6 | |
| SCHEMBL13171279 | 0.75 | TSHR (0.44) | CYP2D6 | |
| SCHEMBL343819 | 0.75 | CA12 (0.50) | CYP2D6 | |
| SCHEMBL24294598 | 0.74 | CYP2D6 (0.47) | CYP2D6 | |
| SCHEMBL23471167 | 0.74 | SAT1 (0.34) | CYP2D6SAT1 | |
| SCHEMBL26490210 | 0.74 | TSHR (0.50) | CYP2D6 | |
| SCHEMBL22848071 | 0.73 | CA12 (0.52) | CYP2D6 | |
| SCHEMBL4957832 | 0.72 | CYP2D6 (0.36) | CYP2D6 | |
| SCHEMBL663749 | 0.71 | SAT1 (0.46) | CYP2D6SAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008109104-A1 | BIVALENT INHIBITORS OF AKT PROTEIN KINASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-09-12 | — | — | WO | disclosed |