Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL859656 | 0.83 | POLB (0.36) | CYP2D6CYP2C19MEN1GAAKMT2A | |
| SCHEMBL9951145 | 0.79 | ANPEP (0.32) | CYP2D6CYP2C19GAA | |
| SCHEMBL29264747 | 0.78 | MEN1 (0.53) | CYP2D6MEN1GAAKMT2A | |
| SCHEMBL2518639 | 0.78 | MEN1 (0.53) | CYP2D6MEN1GAAKMT2A | |
| SCHEMBL19210480 | 0.76 | CYP2D6 (0.48) | CYP2D6CYP2C19MEN1GAAKMT2A | |
| SCHEMBL860015 | 0.75 | POLB (0.32) | — | |
| SCHEMBL25001 | 0.74 | CYP2D6 (0.52) | CYP2D6CYP2C19 | |
| SCHEMBL2460635 | 0.74 | CYP2D6 (0.52) | CYP2D6CYP2C19 | |
| SCHEMBL18954482 | 0.74 | PTGS1 (0.54) | — | |
| SCHEMBL3899246 | 0.73 | CYP2D6 (0.50) | CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008104755-A1 | SUCCINATE DERIVATIVES AND THEIR THERAPEUTIC USE | SERENTIS LIMITED (GB) | 2008-09-04 | — | — | WO | disclosed |