Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746737 | 0.91 | HRH3 (0.52) | HRH3MEN1KMT2A | |
| SCHEMBL21026135 | 0.83 | HRH3 (0.55) | HRH3MEN1KMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7372506 | 0.82 | HRH3 (0.62) | HRH3MEN1KMT2AHRH4KCNH2 | |
| SCHEMBL4743280 | 0.79 | KCNA5 (0.51) | HRH3MEN1KMT2A | |
| SCHEMBL4746716 | 0.79 | HRH3 (0.58) | HRH3MEN1KMT2A | |
| SCHEMBL4743334 | 0.78 | HRH3 (0.55) | HRH3MEN1KMT2A | |
| SCHEMBL4743279 | 0.78 | KCNA5 (0.52) | HRH3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7372502 | 0.78 | HRH3 (0.62) | HRH3MEN1KMT2AHRH4NPC1 | |
| SCHEMBL4743288 | 0.77 | HRH3 (0.56) | HRH3MEN1KMT2AHRH4HRH1 | |
| SCHEMBL4743111 | 0.77 | HRH3 (0.56) | HRH3MEN1KMT2AHRH4HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107320-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | disclosed |