Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.73 |
| ▸ | PPARA | Q07869 | 15/20 | 0.73 |
| ▸ | PPARD | Q03181 | 8/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970285 | 0.94 | PPARG (0.65) | PPARGPPARAPPARD | |
| SCHEMBL7165258 | 0.90 | PPARG (0.69) | PPARGPPARAPPARD | |
| SCHEMBL7165255 | 0.90 | PPARG (0.69) | PPARGPPARAPPARD | |
| SCHEMBL9096482 | 0.89 | PPARG (0.58) | PPARGPPARA | |
| SCHEMBL7162667 | 0.89 | PPARG (0.60) | PPARGPPARAPPARD | |
| SCHEMBL14382157 | 0.88 | PPARG (0.69) | PPARGPPARAPPARD | |
| SCHEMBL12652544 | 0.88 | PPARG (0.69) | PPARGPPARAPPARD | |
| SCHEMBL13722003 | 0.88 | PPARG (0.69) | PPARGPPARAPPARD | |
| SCHEMBL6157782 | 0.88 | FFAR1 (0.65) | PPARGPPARA | |
| SCHEMBL7161623 | 0.88 | PPARG (0.66) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5256670-A | N-aryl-3-aryl-4-substituted-2,3,4,5-tetrahydro-1H-pyrazole-1-carboxamides, insecticidal compositions containing such compounds and methods of controlling insects such compounds | ROHM AND HAAS COMPANY (US) | 1993-10-26 | — | — | US | claimed |
| US-5238908-A | HERBICIDAL GLUTARAMIC ACIDS AND DERIVATIVES | ROHM AND HAAS COMPANY (US) | 1993-08-24 | — | — | US | claimed |
| US-5109014-A | Useful as insecticide or pesticide | DOW AGROSCIENCES LLC, A DELAWARE LIMITED LIABILITY COMPANY | 1992-04-28 | — | — | US | claimed |
| JP-62175473-A | — | — | None | — | — | JP | disclosed |
| JP-7053555-A | — | — | None | — | — | JP | disclosed |
| US-7951793-B2 | Substituted heterocyclic derivatives useful as antidiabetic and antiobesity agents and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-05-31 | — | — | US | disclosed |
| US-7951793-B2 | Substituted heterocyclic derivatives useful as antidiabetic and antiobesity agents and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-05-31 | — | — | US | disclosed |
| EP-1401433-B1 | AZOLE ACID DERIVATIVES, ALONE OR IN COMBINATION, FOR TREATING DIABETES AND DYSLIPIDEMIAS; AND FOR TREATING MALIGNANT DISEASES | BRISTOL MYERS SQUIBB CO (US) | 2010-11-10 | — | — | EP | disclosed |
| US-7579479-B2 | Substituted acid derivatives useful as antidiabetic and antiobesity agents and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-08-25 | — | — | US | disclosed |
| US-7579479-B2 | Substituted acid derivatives useful as antidiabetic and antiobesity agents and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-08-25 | — | — | US | disclosed |
| US-20090076102-A1 | DEUTERIUM-ENRICHED MURAGLITAZAR | PROTIA, LLC (US) | 2009-03-19 | — | — | US | disclosed |
| WO-1992003425-A1 | HYPOGLYCEMIC HYDROXYUREA DERIVATIVES | PFIZER INC. (US) | 1992-03-05 | — | — | WO | disclosed |
| US-5089514-A | 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents | PFIZER INC. (US) | 1992-02-18 | — | — | US | disclosed |
| WO-1991019702-A1 | 3-ARYL-2-HYDROXYPROPIONIC ACID DERIVATIVES AND ANALOGS AS HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1991-12-26 | — | — | WO | disclosed |
| WO-1991007107-A1 | OXAZOLIDINEDIONE HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1991-05-30 | — | — | WO | disclosed |
| EP-0428312-A2 | Oxazolidinedione hypoglycemic agents | PFIZER INC. (US) | 1991-05-22 | — | — | EP | disclosed |
| EP-0177353-B1 | THIAZOLIDINEDIONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1990-04-11 | — | — | EP | disclosed |
| US-4725610-A | TREATMENT OF HYPERLIPEMIA AND DIABETES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-02-16 | — | — | US | disclosed |
| JP-S62175473-A | PRODUCTION OF OXAZOLE DERIVATIVE | TAKEDA CHEM IND LTD | 1987-08-01 | — | — | JP | disclosed |
| EP-0177353-A2 | Thiazolidinedione derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-04-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076102-A1 | DEUTERIUM-ENRICHED MURAGLITAZAR | GIPR, GLP1R, DPP4 | PPARG 143/4885PPARA 206/4885PPARD 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.