Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.60 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.59 |
| ▸ | PPARG | P37231 | 10/20 | 0.56 |
| ▸ | PPARA | Q07869 | 7/20 | 0.56 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.54 |
| ▸ | GYS1 | P13807 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746693 | 1.00 | FFAR1 (0.60) | FFAR1CD274PPARGPPARAPDCD1 | |
| SCHEMBL4747447 | 1.00 | FFAR1 (0.60) | FFAR1CD274PPARGPPARAPDCD1 | |
| SCHEMBL4744019 | 0.98 | FFAR1 (0.58) | FFAR1CD274PPARGPPARAPDCD1 | |
| SCHEMBL4744024 | 0.98 | FFAR1 (0.58) | FFAR1CD274PPARGPPARAPDCD1 | |
| SCHEMBL4746273 | 0.98 | FFAR1 (0.58) | FFAR1CD274PPARGPPARAPDCD1 | |
| SCHEMBL4746214 | 0.97 | CD274 (0.63) | FFAR1CD274PPARGPPARAPDCD1 | |
| SCHEMBL4746225 | 0.97 | CD274 (0.63) | FFAR1CD274PPARGPPARAPDCD1 | |
| SCHEMBL4744622 | 0.94 | FFAR1 (0.62) | FFAR1CD274PPARGPPARAPDCD1 | |
| SCHEMBL4744615 | 0.94 | FFAR1 (0.62) | FFAR1CD274PPARGPPARAPDCD1 | |
| SCHEMBL4743758 | 0.94 | PPARG (0.57) | FFAR1CD274PPARGPPARAPDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | claimed |
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |