Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16322249 | 0.95 | MEN1 (0.61) | MEN1KMT2AALDH1A1HPGDCYP2C9 | |
| SCHEMBL1429699 | 0.90 | MEN1 (0.65) | MEN1KMT2AALDH1A1HPGDCYP2C9 | |
| SCHEMBL7700654 | 0.90 | MEN1 (0.69) | MEN1KMT2AALDH1A1HPGDCYP2C9 | |
| SCHEMBL15480439 | 0.89 | MEN1 (0.68) | MEN1KMT2AALDH1A1HPGDCYP2C9 | |
| SCHEMBL18660186 | 0.89 | MEN1 (0.68) | MEN1KMT2AALDH1A1HPGDCYP2C9 | |
| SCHEMBL7121725 | 0.84 | KMT2A (0.70) | MEN1KMT2AALDH1A1HPGDCYP2C9 | |
| SCHEMBL1520465 | 0.84 | MEN1 (0.84) | MEN1KMT2AALDH1A1HPGDCYP2C9 | |
| SCHEMBL14548190 | 0.84 | MEN1 (0.63) | MEN1KMT2AALDH1A1HPGDCYP2C9 | |
| SCHEMBL853676 | 0.83 | MEN1 (0.65) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL16322460 | 0.83 | MEN1 (0.61) | MEN1KMT2AALDH1A1HPGDCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008122667-A2 | UREYLENE DERIVATIVES | SCHOOL OF PHARMACY (GB) | 2008-10-16 | — | — | WO | disclosed |