Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.69 |
| ▸ | F2 | P00734 | 2/20 | 0.54 |
| ▸ | F11 | P03951 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4686841 | 0.93 | F10 (0.65) | F10F2F11 | |
| SCHEMBL4744598 | 0.92 | F10 (0.61) | F10F2F11 | |
| SCHEMBL4748459 | 0.88 | F10 (0.67) | F10F2F11 | |
| SCHEMBL4854345 | 0.88 | F10 (0.69) | F10F2F11 | |
| SCHEMBL4744636 | 0.85 | F10 (0.70) | F10F2F11 | |
| SCHEMBL5432192 | 0.85 | F10 (0.69) | F10F2F11 | |
| SCHEMBL5429200 | 0.85 | F10 (0.68) | F10F2F11 | |
| SCHEMBL5447278 | 0.84 | F10 (0.69) | F10F2F11 | |
| SCHEMBL5434818 | 0.84 | F10 (0.58) | F10F2F11 | |
| SCHEMBL5437921 | 0.83 | F10 (0.69) | F10F2F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603572-A4 | LACTAM-CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2008-06-25 | — | — | EP | disclosed |
| EP-1603572-A1 | LACTAM-CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS | Bristol-Myers Squibb Company (US) | 2005-12-14 | — | — | EP | disclosed |
| WO-2004082687-A1 | LACTAM-CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-09-30 | — | — | WO | disclosed |