Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.55 |
| ▸ | PPARA | Q07869 | 6/20 | 0.55 |
| ▸ | PPARD | Q03181 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747139 | 1.00 | PPARG (0.55) | PPARGPPARAPPARDKDM4ELTA4H | |
| SCHEMBL4744877 | 0.98 | PPARG (0.54) | PPARGPPARAPPARDKDM4ELTA4H | |
| SCHEMBL4744879 | 0.98 | PPARG (0.54) | PPARGPPARAPPARDKDM4ELTA4H | |
| SCHEMBL4748466 | 0.93 | PPARA (0.54) | PPARGPPARAPPARDKDM4ELTA4H | |
| SCHEMBL4743913 | 0.93 | PPARA (0.54) | PPARGPPARAPPARDKDM4ELTA4H | |
| SCHEMBL4743905 | 0.93 | PPARA (0.54) | PPARGPPARAPPARDKDM4ELTA4H | |
| SCHEMBL4748385 | 0.92 | PPARG (0.58) | PPARGPPARAPPARDKDM4EKMT2A | |
| SCHEMBL4748383 | 0.92 | PPARG (0.58) | PPARGPPARAPPARDKDM4EKMT2A | |
| SCHEMBL4744764 | 0.92 | KDM4E (0.53) | PPARGPPARAPPARDKDM4ELTA4H | |
| SCHEMBL4744766 | 0.92 | KDM4E (0.53) | PPARGPPARAPPARDKDM4ELTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |