Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.54 |
| ▸ | PELP1 | Q8IZL8 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | USP10 | Q14694 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354751 | 0.94 | AR (0.55) | ARPELP1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL222905 | 0.89 | AKR1C3 (0.61) | ARPELP1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL11949145 | 0.87 | AR (0.58) | ARPELP1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL221362 | 0.87 | AR (0.61) | ARPELP1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL6870341 | 0.86 | AKR1C3 (0.56) | ARPELP1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL8169431 | 0.86 | AR (0.60) | ARPELP1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL1346767 | 0.85 | AR (0.61) | ARPELP1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL8887657 | 0.85 | AR (0.58) | ARPELP1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7618685 | 0.84 | AR (0.58) | ARPELP1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL4288702 | 0.84 | AR (0.57) | ARPELP1AKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107365-A1 | NEW COMPOUNDS | MEDIVIR AB (SE) | 2008-09-12 | — | — | WO | disclosed |