Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | KDR | P35968 | 1/20 | 0.58 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 12/20 | 0.51 |
| ▸ | PPARG | P37231 | 11/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747305 | 1.00 | POLB (0.59) | POLBKDRCD274MEN1KMT2A | |
| SCHEMBL4747374 | 0.98 | KDR (0.58) | POLBKDRCD274MEN1KMT2A | |
| SCHEMBL4748578 | 0.98 | KDR (0.58) | POLBKDRCD274MEN1KMT2A | |
| SCHEMBL4747378 | 0.98 | KDR (0.58) | POLBKDRCD274MEN1KMT2A | |
| SCHEMBL4746276 | 0.96 | KDR (0.57) | POLBKDRCD274MEN1KMT2A | |
| SCHEMBL4746275 | 0.96 | KDR (0.57) | POLBKDRCD274MEN1KMT2A | |
| Methane SCHEMBL4788111 | 0.94 | POLB (0.53) | POLBKDRCD274MEN1KMT2A | |
| SCHEMBL4744001 | 0.93 | CD274 (0.65) | POLBKDRCD274MEN1KMT2A | |
| SCHEMBL4743927 | 0.93 | CD274 (0.65) | POLBKDRCD274MEN1KMT2A | |
| SCHEMBL4744825 | 0.92 | POLB (0.53) | POLBKDRMEN1KMT2APPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |