Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15255586 | 1.00 | HTT (0.47) | HTTMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10106882 | 0.87 | HTT (0.48) | HTTMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10101968 | 0.87 | SMN1; SMN2 (0.46) | HTTMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10107082 | 0.85 | HTT (0.45) | HTTMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL15251323 | 0.82 | HTT (0.42) | HTTMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL15251319 | 0.78 | HTT (0.39) | HTTMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL15251318 | 0.78 | HTT (0.39) | HTTMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL15251330 | 0.78 | HTT (0.39) | HTTMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10107043 | 0.78 | HTT (0.51) | HTTMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10107086 | 0.77 | HTT (0.53) | HTTMAPTSMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8536157-B2 | Non-steroidal compounds | THE UNIVERSITY OF MELBOURNE (AU) | 2013-09-17 | — | — | US | disclosed |
| WO-2008124878-A1 | NON-STEROIDAL COMPOUNDS | CRYPTOPHARMA PTY LTD (AU) | 2008-10-23 | — | — | WO | disclosed |