Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.53 |
| ▸ | PPARA | Q07869 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4748103 | 1.00 | PPARG (0.53) | PPARGPPARAPOLBMAPTTP53 | |
| SCHEMBL4746707 | 0.95 | PPARG (0.55) | PPARGPPARAPOLBMAPTTP53 | |
| SCHEMBL4746709 | 0.95 | PPARG (0.55) | PPARGPPARAPOLBMAPTTP53 | |
| SCHEMBL4747915 | 0.93 | FFAR1 (0.55) | PPARGPPARAMAPTKMT2AFFAR1 | |
| SCHEMBL4747946 | 0.93 | FFAR1 (0.55) | PPARGPPARAMAPTKMT2AFFAR1 | |
| SCHEMBL4747918 | 0.93 | FFAR1 (0.55) | PPARGPPARAMAPTKMT2AFFAR1 | |
| SCHEMBL4744477 | 0.93 | FFAR1 (0.57) | PPARGPPARAMAPTFFAR1LTA4H | |
| SCHEMBL4744427 | 0.93 | FFAR1 (0.57) | PPARGPPARAMAPTFFAR1LTA4H | |
| SCHEMBL4744421 | 0.93 | FFAR1 (0.57) | PPARGPPARAMAPTFFAR1LTA4H | |
| SCHEMBL4743765 | 0.91 | PPARG (0.57) | PPARGPPARAPOLBMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | claimed |
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |