Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.60 |
| ▸ | PPARA | Q07869 | 15/20 | 0.57 |
| ▸ | PPARD | Q03181 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4748313 | 1.00 | PPARG (0.60) | PPARGPPARAPPARD | |
| SCHEMBL4748485 | 0.98 | PPARG (0.62) | PPARGPPARAPPARD | |
| SCHEMBL4748488 | 0.98 | PPARG (0.62) | PPARGPPARAPPARD | |
| SCHEMBL4748482 | 0.96 | PPARG (0.63) | PPARGPPARAPPARD | |
| SCHEMBL4745027 | 0.96 | PPARG (0.63) | PPARGPPARAPPARD | |
| SCHEMBL4746273 | 0.92 | FFAR1 (0.58) | PPARGPPARA | |
| SCHEMBL4744019 | 0.92 | FFAR1 (0.58) | PPARGPPARA | |
| SCHEMBL4744024 | 0.92 | FFAR1 (0.58) | PPARGPPARA | |
| SCHEMBL4862900 | 0.91 | PPARG (0.57) | PPARGPPARAPPARD | |
| SCHEMBL4746302 | 0.91 | PPARG (0.58) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | claimed |
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |