Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL643530 | 0.87 | CHRM3 (0.56) | CHRM3 | |
| SCHEMBL4751956 | 0.86 | CHRM3 (0.52) | CHRM3 | |
| SCHEMBL3298620 | 0.85 | CHRM3 (0.59) | CHRM3 | |
| SCHEMBL643048 | 0.82 | CHRM3 (0.51) | CHRM3 | |
| SCHEMBL644248 | 0.79 | CHRM2 (0.59) | CHRM3 | |
| SCHEMBL3535978 | 0.77 | CHRM3 (0.63) | CHRM3 | |
| SCHEMBL643200 | 0.76 | CHRM2 (0.56) | CHRM3 | |
| SCHEMBL643688 | 0.75 | CHRM3 (0.50) | CHRM3 | |
| SCHEMBL643348 | 0.75 | CHRM2 (0.74) | CHRM3 | |
| SCHEMBL943879 | 0.74 | CHRM3 (0.58) | CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893577-A1 | BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | Theravance, Inc. (US) | 2008-03-05 | — | — | EP | claimed |
| WO-2006138218-A1 | BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | THERAVANCE, INC. (US) | 2006-12-28 | — | — | WO | claimed |